Lilly

Analytical Chemistry Research Advisor - Synthetic Molecule Design and Development (SMDD)

Indianapolis

FULL TIME

November 16, 2024

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Synthetic Molecule Design and Development (SMDD) organization is responsible for the development of synthetic drug substances and drug products from the pre-clinical phase through commercialization. Our scientists and engineers develop innovative technical solutions to advance an exciting portfolio that includes small molecules, peptides, oligonucleotides, and other emerging therapeutic modalities. By encouraging a hardworking, culturally diverse workforce that exhibits deep technical expertise, SMDD delivers on these responsibilities and helps bring the next generation of life-changing medicines to patients!

SMDD has an exciting opportunity for an Analytical Chemistry Research Advisor to join our multidisciplinary team of chemists, engineers, and formulation scientists. Empowered by access to world-class capabilities and extensive pharmaceutical development experience, you will help deliver technical solutions that enable deeper understanding of processes and products across the portfolio. Ideal candidates will possess experience across multiple analytical techniques (e.g., UHPLC, mass spectrometry, IR, Raman, UV, NMR), demonstrate an aptitude in technical problem-solving, and be motivated to work both independently and collaboratively in a dynamic environment.

Position Responsibilities:
  • Enable the design, development, and implementation of analytical methodologies for the characterization and analysis of oligonucleotides, peptides, and small molecules.
  • Contribute to the establishment of robust control strategies through generation of data, development of analytical methods, and collaboration with internal and external development partners.
  • Demonstrate proficiency in multiple modes of chromatography, mass spectrometry, optical spectroscopy, instrument engineering, or other analytical technologies.
  • Develop strategies for instrument integration with automated data analysis workflows and process sampling interfaces.
  • Engage with scientists across development and manufacturing to develop a deep understanding of new initiatives and improve existing scientific processes.
  • Identify ground-breaking analytical technologies as well as trends in analytical chemistry, synthetic chemistry, and chemical engineering.
  • Identify and exploit new scientific concepts, strong problem-solving skills, and be self-motivated to contribute across multiple projects.
  • Demonstrate strong written and verbal communication skills to speak to both technical and business-related implications of your work.

Basic Qualifications:
  • Ph D in Analytical Chemistry, Biochemistry, Chemistry, or related field.

Additional Skills/Preferences:
  • Reversed phase chromatography, ion exchange chromatography, size exclusion chromatography, chiral chromatography, gas chromatography.
  • Hands-on experience with mass spectrometry in the characterization and quantitation of synthetic molecules including oligonucleotides, peptides, and small molecules.
  • Experience with data interpretation, including the application of chemometrics, multivariate modeling, and other data manipulation tools.
  • Learning agility and demonstrated ability to apply technical knowledge to improve the understanding of chemical systems or improve analytical techniques.
  • Ability to balance multiple activities, prioritize evolving project needs, and handle ambiguity.

Additional Information:
  • Possible exposure to chemicals, allergens, and loud noises
  • Occasional travel (0 to 10%)
  • Position Location: Indianapolis, IN; Lilly Technology Center-North (LTC-N)

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.


Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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