Summit Therapeutics (Summit) Mission
To build a viable, long-lasting health care organization that assumes full responsibility for designing, developing, trial execution and enrollment, regulatory submission and approval, as well as successful commercialization of patient, physician, caregiver, and societal-friendly medicinal therapy intended to: improve quality of life, increase potential duration of life, and resolve serious medical healthcare needs. To identify and control promising product candidates based on exceptional scientific development and administrational expertise, develop our products in a rapid, cost-efficient manner, and to engage commercialization and/or development partners when appropriate.
We accomplish this by building a team of world class professional scientists and business administrators that apply their experience and knowledge to this mission.
Summit Activities
We have in-licensed Ivonescimab, which is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule.
We initiated phase-III clinical studies in Europe and in North America in the following NSCLC indications:

• Ivonescimab combined with chemotherapy in patients with epidermal growth factor receptor (EGFR)-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a third-generation EGFR tyrosine kinase inhibitor (“HARMONi”)
• Ivonescimab combined with chemotherapy in first-line metastatic squamous NSCLC patients (“HARMONi-3”)
• Ivonescimab in first-line PD-L1 High, Metastatic NSCLC (“HARMONi-7”)

Ivonescimab is an investigational therapy that is not approved by any regulatory authority other than China’s National Medical Products Administration (NMPA).

Overview of Role:
The Medical Director, Europe, is a highly motivated and experienced scientific expert specializing in Immuno-Oncology. Reporting to the Head of Global Medical Affairs, the Director will oversee the Medical Science Liaisons (MSL) team in Europe. Key responsibilities include engaging in meaningful peer-to-peer scientific dialogue with Key Opinion Leaders (KOLs), payers, investigators, and other healthcare providers within the European healthcare system. The Director will develop both country-specific and regional medical affairs strategies to support the clinical development program and product lifecycle from Phase III through pre-launch, launch, and post-launch activities. Combining strong business acumen, clinical expertise, and market awareness, the Director will act as a vital conduit of information gathered by the MSL team to various stakeholders within Summit. This remote, regional role anticipates that the Director will spend 70% of their time in the field, interacting with external stakeholders, overseeing the MSLs, and maintaining a high level of therapeutic expertise.

Role and Responsibilities:

• Develop and execute medical strategies for clinical studies success and product prelaunch across European markets, ensuring alignment with regulatory requirements and company objectives
• Manage the MSL team and oversee their strategic territory planning, including KOL, HCP, and Investigator engagement plans. Ensure alignment with Summit medical and development objectives, and drive for excellence in execution focusing on quality.
• Directly and via the MSLs Identify, gain access to, and develop professional, customer-centric relationships with European experts in Immuno-Oncology
• Lead and participate in educational programs, symposiums, and advisory boards to communicate scientific insights and support product positioning
• Ensure all medical activities align with regional regulations and ethical standards.
• Participate, monitor, and provide scientific insights relevant to Summit
• Create, maintain, and collaborate with cross-functional stakeholders to develop and execute activities designed to support and meet shared scientific or business objectives
• Initiate and oversee all medical affairs activities in Europe (e.g., advisory boards, Masterclasses, Round-tables, congress engagement)
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Doctoral degree in health sciences from an accredited university (MD, Ph D, Pharm D, or equivalent)
• Lung Cancer clinical experience within the last 5 years is highly desired
• A minimum of 10+ years of clinical, scientific, research, or industry-related experience required
• Experience as a Medical Science Liaison or equivalent field role is required
• Previous pharmaceutical industry experience within a relevant scientific discipline is required
  • Proficiency in English is required. Additional European language skills are a plus.
• The Director must possess and demonstrate past achievements in:
  • Understanding, analyzing, and communicating complicated scientific concepts and data
  • Building credible relationships with prominent HCPs
  • Independently identifying and translating corporate needs into action plans that achieve objectives
  • Good management skills. Demonstrated ability to guide, support and motivate highly sophisticated employees.
  • Self-motivation to achieve and exceed goals
  • Problem-solving and analytic skills
  • Critical thinking
  • Ability to work independently
• Other essential requirements:
  • Meeting healthcare industry representative (HCIR) credentialing requirements to enter facilities and organizations within the assigned territory. These may include background checks, drug screens, and proof of immunization/vaccination for various diseases.
  • Willingness to travel 70% of the time
  • Proficiency in using the standard MS Office suite (e.g., Word, Excel), electronic document management systems, and document review tools
  • Strong computer and database skills
  • Attention to detail, accuracy, and confidentiality
  • Clear and concise oral and written communication skills
  • Excellent organizational skills
  • Ability to effectively multi-task or adapt quickly to changing priorities
  • Ability to manage time-sensitive and highly confidential documents
  • Ability to prioritize conflicting demands
  • Ability to work in a fast-paced, demanding, and collaborative environment